Bound States and the Special Composition Question

The Special Composition Question asks under what conditions a plurality of objects form another, composite object. We propose a condition grounded in our scientific knowledge of physical reality, the essence of which is that objects form a composite object when and only when they are in a bound state – whence our Bound State Proposal. We provide a variety of reasons in favour of a mereological theory that accommodates our Proposal. We consider but reject another proposal, which is quantum-physical in nature: the Entanglement Proposal. We close by responding to Teller’s ‘Suit Objection’

Gene Regulation in the Pi Calculus: Simulating Cooperativity at the Lambda Switch

Part of the Lecture Notes in Computer Science book series (LNCS, volume 4230).Also part of the Lecture Notes in Bioinformatics book sub series (volume 4230).International audienceWe propose to model the dynamics of gene regulatory networks as concurrent processes in the stochastic pi calculus. As a first case study, we show how to express the control of transcription initiation at the lambda switch, a prototypical example where cooperative enhancement is crucial. This requires concurrent programming techniques that are new to systems biology, and necessitates stochastic parameters that we derive from the literature. We test all components of our model by exhaustive stochastic simulations. A comparison with previous results reported in the literature, experimental and simulation based, confirms the appropriateness of our modeling approach